Difference between Melanotan 1 and 2

Oct 18, 2011 by

Difference between Melanotan 1 and 2

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  1. khristine

    In order to know the differences between malatonan 1 and 2, it is best to get familiarize with some of the basic terminologies in relation to it. First off, melanotan in its general form is a synthetically researched and formulated peptides that resembles the functioning of a commonly occurring hormone known as melanocyte stimulating hormone or simply a-MSH.

    a-MSH is a hormone that primarily stimulates the creation and discharge of melanin produced by the malanocytes within the skin and hair especially when exposed to UV light. Melanin is the substance that is present within our skin and hair that gives it natural color. On the other hand, melanocytes refer to the cells that naturally produce melanin within the body. Now that these terminologies are clear, it is easy to distinguish melanotan 1 and 2.

    Melanotan as a peptide is classified into melanotan 1 (also known as MT 1 or afamelanotide) and melanotan 2 (or MT II). Both are drugs intended for skin tanning even without being exposed to UV light. As drugs, both are also used and marketed for treatment of various disorders.

    Melanotan 1 is developed by an Australian based pharmaceutical company under the name Clinuvel. The drug is used as a preventive treatment for skin cancer and other light related skin disorders with the likes of Actinic Keratosis (also known as solar keratosis or simply AKs) and polymorphous light eruption (or simply PMLE/PLE). The said conditions defines the intolerant reaction of the skin towards UV light which is characterized by symptoms of lumps, itching, severe sores, burning sensations, and/or dry skin.

    Malanotan 2, in comparison, is developed by an American company under the name Palatin Technologies Inc. The drug is licensed under the name Bremelanotide and is being used for possible cure of sexual dysfunctions, more particularly ED or erectile dysfunction that is common among men.

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